In rare cases, acetaminophen can cause a severe skin reaction that can be fatal. Call your doctor immediately if you experience any of the following side effects:. The half-life of a medication is the time it takes for the drug to decrease to half of its original concentration, or put another way, the time it takes for half of a dose to be eliminated from the body.
The half-lives of the components of Tylenol 3 are slightly different:. Urine screenings, which are the most commonly used drug tests because they are relatively easy and cost-effective to administer, can detect the codeine in Tylenol 3 in your system for up to three days after use.
Blood tests, which are used less frequently because they are more invasive and costly than urine tests, have a hour window for detecting the codeine in Tylenol 3.
Codeine in Tylenol 3 is detectable in oral fluid taken in saliva testing for up to four days after ingestion. Codeine use can be detected by a hair follicle test for a longer period—up to three months. If you consume just one poppy seed muffin or two poppy seed bagels, it can trigger a false-positive test result for opiates. Poppy seeds contain trace amounts of codeine. Certain medications, including certain allergy and cold medications diphenhydramine , sleep aids doxylamine , and medications to treat hypertension Verapamil , have been found to cause false-positives for opiates on enzyme immunoassay EIA drug tests as well.
It's important to let the lab clinician know if you have eaten anything or taken any medications or supplements that might affect your results. How long Tylenol 3 is detectable in your body depends on a variety of factors, including the dosage and how often you use the medication as well as your weight, age, metabolism, and overall health. Older adults tend to clear the drug at a slower pace than younger adults. Your metabolic rate, which can be influenced by age, activity level, and overall health, influences the detection time of Tylenol 3.
In general, the slower your metabolism, the longer the drug will remain in your system. Because the liver and kidneys both play a role in the metabolism of the drug, impaired liver and kidney function can mean that it takes longer to metabolize Tylenol 3. A higher dose of Tylenol 3 will take longer to process and excrete than a lower dose. Similarly, if you've been taking the drug for some time, it will take longer to clear your system.
Like other drugs, the best way to get Tylenol 3 out of your system is to stop using the drug and give your body time to process and eliminate it. Staying well-hydrated and getting regular exercise can't hurt but this doesn't mean that sweating out or flushing out the drug with tons of water will help.
This method will only dilute the drug test and you'll likely have to retake it. If you plan to stop using the drug, work with your doctor. It's best to taper off of prescriptions containing codeine in order to avoid unpleasant withdrawal symptoms. Codeine also can be extremely dangerous if there's too much of the drug in the body at once, whether it's taken alone or as an active ingredient in Tylenol 3. The same may be true of acetaminophen even though it's a non-narcotic pain reliever, but for different reasons.
If you take the medication exactly as your doctor prescribed and you're careful to not take another drug that could interact with acetaminophen or codeine, you shouldn't have any problems taking Tylenol 3. Still, it's good to be aware of the following symptoms of a potential overdose:. Symptoms of Tylenol 3 overdose may not be evident right away, but may include:. If you suspect that you or a loved one may be experiencing an overdose, call or seek medical help immediately. Acetaminophen has a narrow safety range.
If you take more than 4, milligrams per day, you risk irreversible liver damage that ultimately can lead to death. Damage and overdose can happen more easily than you might think because acetaminophen is an ingredient in many different combination medications, such as cold or allergy drugs designed to target multiple symptoms.
For this reason, combination medications like Tylenol 3 are limited to no more than milligrams of acetaminophen per tablet, capsule, or other dosage unit. Before you take another medication, read the ingredient list carefully. If the medication contains acetaminophen or paracetamol as it's known in Europe and the UK , note how many milligrams there are per dose. Do the math to make sure you don't exceed 4, milligrams in a hour period.
Safer yet, talk to your doctor or pharmacist before taking Tylenol 3 and another product containing acetaminophen. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines.
If too much of this medicine is taken for a long time, it may become habit-forming causing mental or physical dependence or cause an overdose. Also, large amounts of acetaminophen may cause liver damage if taken for a long time. It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of acetaminophen and codeine combination.
This medicine should also come with a Medication Guide. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions. Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen.
It is not safe to use more than 4 grams 4, milligrams of acetaminophen in one day 24 hours , as this may increase the risk for serious liver problems. Shake the oral suspension well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup.
The average household teaspoon may not hold the right amount of liquid. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of the oral solution or tablet, skip the missed dose and go back to your regular dosing schedule. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. Acetaminophen and codeine combination oral solution or tablet can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong narcotic pain medicines. Make sure you store the medicine in a safe and secure place to prevent others from getting it. Drop off any unused narcotic medicine at a drug take-back location right away.
If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations.
Here is the link to the FDA safe disposal of medicines website:www. It is very important that your doctor check your or your child's progress while you are taking this medicine, especially within the first 24 to 72 hours of treatment. This will allow your doctor to see if the medicine is working properly and to decide if you or your child should continue to take it.
Blood tests may be needed to check for unwanted effects. It is against the law and dangerous for anyone else to use your medicine. Keep your unused medicine in a safe and secure place. People who are addicted to drugs might want to steal this medicine. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. If you think you or someone else may have taken an overdose of this medicine, get emergency help at once.
Signs of an overdose include: dark urine, difficult or trouble breathing, irregular, fast or slow, or shallow breathing, nausea, vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, or yellow eyes or skin. This medicine may cause sleep-related breathing problems eg, sleep apnea, sleep-related hypoxemia. Your doctor may decrease your dose if you have sleep apnea stop breathing for short periods during sleep while using this medicine.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem. Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal withdrawal syndrome in your newborn baby. You can help remember when to take your medicines and how much to take by:. Some people may take acetaminophen with codeine because it makes them feel high.
A breastfeeding baby can overdose on acetaminophen with codeine if their mother is taking the medicine. Nursing mothers taking acetaminophen with codeine should consider bottle-feeding their babies. Call or the National Poison Control Center and listen carefully to their instructions. They may send emergency medical care. Someone who has overdosed on acetaminophen with codeine could be sent to the hospital.
If your liver is affected, recovery could take longer. Long-term liver damage is possible because toxins are released into your system when acetaminophen is broken down into other chemicals by your liver. Long-term use can cause dependency and addiction to the drug. Codeine and hydrocodone both treat pain, but one may be better suited for you depending on the severity of your pain.
Learn about the most addictive prescription drugs, including Adderall and Xanax. Codeine is an opiate used to treat pain or cough. Learn what to expect from withdrawal if you become dependent on or addicted to codeine. Find information on isopropyl alcohol poisoning symptoms, causes, and diagnosis.
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